Join our team, Change the world

Location:Rehovot, Science Park, Israel

About the Position:

Emendo is a leading CRISPR company developing disruptive gene editing technology to cure severe genetic diseases and cancer. We are looking for a motivated Software Developer to join our growing Computational Biology department within the R&D. The department works very closely with our scientific departments, as we aim to combine the lab scientists’ experimental data with our computational skills to promote research.

The position requires adaptability, creativity, and aspiration for constant innovation in pursuit of company goals.

The environment is exciting, fast-paced and offers the opportunity to work at the forefront of gene editing research. If you seek a meaningful job, working with great colleagues using cutting edge science – this is your opportunity.

JOB DESCRIPTION

• Build the Computational Biology department’s infrastructure, such as: bioinformatic pipelines, common software packages, CI/CD tools, etc.
• Enforce coding standards and other software development best practices
• Manage the company central database
• Build other computational tools according to the needs of the various R&D biology departments

REQUIRED

• BSc or MSc in computer science, computational biology, bioinformatics, or related fields
• 3-5 years of related work experience as a software developer
• Excellent Python programming skills
• Experience with Linux environment
• Experience with SQL and non-SQL databases

DESIRED SKILLS

• Good knowledge and understanding of biological fundamentals
• Experience designing, developing, deploying, and CI/CD in a DevOps environment
• Experience with Docker containers or other types of Container technologies
• Experience with bioinformatic pipeline tools such as Nextflow or Snakemake
• Experience with AWS or other cloud environments

Apply Here

Location:Rehovot, 1 Holtzman St. Science Park, Israel

About the Position:

Emendo Biotherapeutics is developing a transformative high precision gene editing technology and genome-engineering based therapeutics to cure severe genetic diseases. We are seeking a talented computational structural biologist with strong expertise in protein modeling, engineering and design to join our computational biology team within the R&D. This is a rare opportunity to join a company with a rapid growth and make an impact in an innovative cutting-edge field.

Responsibilities 

• Work with protein modeling platforms and tools to perform 3D modeling and design of DNA-RNA-protein complexes
• Gain deep structural insights into Emendo’s growing collection of novel gene editing tools and suggest ways to enhance their activities focusing on therapeutic goals

• Conduct protein and RNA structural optimization
• Develop new biomolecular machine learning tools

Required

• PhD in structural biology, computational biophysics or related fields with 3+ years of experience
• Extensive experience and knowledge in macromolecular modeling and rational design techniques and tools. This applies to proteins, RNA and DNA 2D and 3D structures and structure-function relationship determination
• Experience with RosettaCommons for protein engineering
• Experience with one or more macromolecular modeling software platforms (PyMol, UCSF Chimera, Schrodinger, etc.)
• Programming experience in Python
• Extensive experience in Linux OS

Desired Skills

• Ability to conduct protein mutation analysis
• Experience with molecular dynamics (MD) simulations engines (GROMACS, AMBER or NAMD)
• Experience working in a cloud environment
• Experience in developing machine learning models (SVM, k-means, logistic regression)

Apply Here

Location:Rehovot, 1 Holtzman St. Science Park, Israel

About the Position:

Emendo is a leading CRISPR company developing disruptive gene editing technology to cure severe genetic diseases and cancer. We are looking for a motivated Scientist to join our Analytical team. This team develops and uses cutting edge molecular technologies to identify and characterize genomic editing events using high throughput automated systems.

The successful candidate will take a central part in our efforts to assess novel gene-editing tools and characterize cell-therapy drug products as well as support our R&D efforts with professional analytical skills. The position requires adaptability, multitasking skills, creativity, and capacity for constant innovation in pursuit of company goals.

The environment is exciting, fast-paced and offers the opportunity to work at the cutting edge of cellular engineering research. If you seek a meaningful job, working with great colleagues using cutting edge science – this might be your opportunity.

Responsibilities

• Design and perform experiments aimed at measuring genomic events
• Record, analyze and present experimental data
• Process Next Generation Sequencing samples using a robotic system.
• Write detailed protocols, SOPs and reports.
• Work cross-functionally with other groups
• Design and develop new genomic methods, troubleshoot, and improve existing methods
• Maintain expertise in the field by staying current to relevant literature.

Requirements:

• MSc with at least 2 years of experience or PhD in Life sciences.
• Vast experience in molecular biology techniques.
• Experience operating liquid-handling robotics systems (Preferred systems include, Beckman, Tecan or similar) – highly desired
• Hand-on experience with Next Generation Sequencing sample preparation and data analysis – highly desired
• Experience with ddPCR or tissue culture –advantage
• Good communication skills.
• Team player, capable of leading processes with teams in a constructive and effective way.

Apply Here

Location:Rehovot, 1 Holtzman St. Science Park, Israel

About the Position:

Emendo is developing a transformative gene editing technology to cure severe genetic diseases. We are looking for a motivated PhD level Scientist to join our  pre-clinical research team. If you seek a meaningful Job, working with great colleagues using cutting edge science – this might be your opportunity.

The successful candidate will take a central part in our efforts to develop and assess our genome editing strategies, both at the genomic and functional levels, for the treatment of variety of genetic disorders. The project involves defining and characterization of the editing composition by functional assays in the relevant cell system to determine safety and efficacy. The position requires adaptability, creativity, and capacity for constant innovation in pursuit of company goals. The environment is exciting, fast-paced and offers the opportunity to work at the cutting edge of cellular engineering research.

Responsibilities

• Conceive, design, and perform experiments independently.
• Lead projects with CROs in Israel and abroad.
• Record, analyze and present experimental data
• Work cross-functionally with other groups

Qualifications & Skills

• Ph.D. degree in Biology or other relevant discipline (Experience in the industry is an advantage).
• Ms.C. in Biology or relevant discipline with 3-5 years’ experience in industry
• Good social skills, hard worker and capable of performing on a tight schedule.
• Demonstrated experience in the followings:
  • Developing and troubleshooting methodologies.
  • Tissue culture skills (Required)
  • Flow cytometry (Required)
  • Packaging of Lentivirus and rAAV (advantage).
  • Genomic manipulations of primary cells by nucleofection and transduction (advantage).
  • ddPCR and NGS (advantage).

Apply Here

Location:Rehovot, 1 Holtzman St. Science Park, Israel

About the Position:

Emendo is a gene editing company focused on developing potentially curative treatments for patients with severe genetic diseases. We are looking for a motivated and enthusiastic individual, experienced in molecular biology and biochemistry, to join our Nuclease Technology department. The successful candidate will take part in the team’s effort to optimize engineered nucleases using in-vitro as well as cell-based enzymatic assays.

The environment is exciting, fast-paced and offers the opportunity to work at the cutting edge of cellular engineering R&D. If you seek a meaningful job, working with great colleagues using cutting edge science – this might be your opportunity.

Responsibilities:

• Perform molecular and biochemical assays for characterizations of selected nucleases in multiple systems (E. Coli and different mammalian cell-lines).

• Work collaboratively with other groups.
• Stay up to date with relevant scientific literature.
• Compile and present data of test methods, technical reports, and support procedures for new and existing methods.
• Document and report results in accordance with the company’s policy.
• Perform complex experiments with strong attention to details and documentation.
• Accomplish goals within strict defined timelines.

Qualifications & Skills:

• MSc degree in a life science discipline such as biochemistry, molecular biology, biotechnology or related disciplines.
• Experience and knowledge in: Protein biochemistry, biophysical methods for protein characterization, enzymology, molecular biology – Advantage.
• Motivated, responsible scientist with a strong attention to details and knowledge of efficient experimental design and documentation.
• Ability to work both independently and as part of a team.
• Data analysis skills using Excel, Prism, Origin, or a similar program.
• Excellent time management and organizational skills.
• Fluent in English, both oral and written.